SLC16A1

Across TCGA patient cohorts, SLC16A1 mutation is significantly associated with the RNA expression of many other genes, with 4,943 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC16A1-associated genes across cancer lineages are RNU6-1180P, MIR4427, and RNA5SP297. Each is linked with SLC16A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC16A1-to-partner and partner-to-SLC16A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1180P grouped by SLC16A1-low versus SLC16A1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A1→partner) and Y-score (partner→SLC16A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-1180P →	+0.292	+6.293	<.001	<.001	3	3
LUSC	MIR4427 →	+0.649	+3.438	<.001	<.001	3	3
UCEC	RNA5SP297 →	+0.347	+1.627	<.001	.002	3	3
UCEC	NDUFS4 →	+0.439	+2.247	.001	.001	3	3
UCEC	PRDX3 →	+0.441	+2.254	.006	.005	3	3
UCEC	ENTR1 →	+0.519	+2.850	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,943 associations by consensus.

RNU6-1180P by SLC16A1 expression — BRCA

Explore this box plot interactively →