SLC16A1

Across TCGA cell cohorts, SLC16A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,082 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SLC16A1-associated GO terms across cancer lineages are Pyruvate catabolic process, Nuclear pore complex assembly, and IMP biosynthetic process. Each is linked with SLC16A1 in more than 12 cancer types. Because this analysis shows association rather than direction, both SLC16A1-to-partner and partner-to-SLC16A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyruvate catabolic process grouped by SLC16A1-low versus SLC16A1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC16A1→partner) and Y-score (partner→SLC16A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Pyruvate catabolic process →	+0.216	+1.388	<.001	<.001	3	13
BLOOD_Lymphoma	Nuclear pore complex assembly →	+0.120	+1.145	<.001	<.001	3	12
BREAST	IMP biosynthetic process →	+0.162	+2.985	<.001	<.001	3	11
BONE	Positive regulation of mRNA splicing, via spliceosome →	+0.150	+1.109	<.001	<.001	3	11
BONE	rRNA metabolic process →	+0.093	+0.873	.007	.004	3	11
BONE	Nucleolar large rRNA transcription by RNA polymerase I →	+0.143	+1.113	.002	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,082 associations by consensus.

Pyruvate catabolic process by SLC16A1 expression — LUNG_SCLC

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