SLC16A1-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SLC16A1-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated SLC16A1-AS1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SLC16A1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC16A1-AS1 expression acts as an unfavorable survival marker, although some lineages such as READ and SKCM show a favorable association.

UCEC, KICH, and KIRC are the cancer types where SLC16A1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSMedianAll0.5630.728<.001104view →
KICHDFSMedianIII,IV0.2360.947<.001101view →
KIRCDFSMedianAll0.4960.721<.00198view →
THCADFSTertileIII,IV0.4790.840<.00178view →
LIHCDFSMedianAll0.4660.616<.00174view →
COADDFSMedianAll0.7010.852.00258view →
LGGDFSMedianAll0.6150.860<.00154view →
ACCDFSTertileAll0.6070.965.00549view →
BLCADFSQuartileAll0.5070.726<.00145view →
SARCOSTertileAll0.3720.662<.00140view →
LAMLDFSMedianAll0.4630.672.00136view →
READOSMedianII,III,IV0.8770.328.00227view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

Exploration