Across TCGA pan-cancer cohorts, SLC15A5 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of SLC15A5’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where SLC15A5 RNA is repressed in tumor relative to normal tissue. In most cancer types SLC15A5 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KICH, KIRC, and BRCA are the cancer types where SLC15A5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC15A5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−0.038	<.001	7	view →
KIRC	All	All	+0.035	.002	7	view →
BRCA	All	III,IV	−0.301	<.001	6	view →
LUSC	All	II,III,IV	−0.026	.014	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: SLC15A5 RNA expression & survival · all SLC15A5 data types