SLC15A2

Across TCGA pan-cancer cohorts, SLC15A2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SLC15A2 data layer compared with 17 for mass-spec protein and 11 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SLC15A2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC15A2 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, LSCC, and CCRCC are the cancer types where SLC15A2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	All	0.962	0.745	.021	10	view →
LSCC	OS	Tertile	III,IV	0.855	0.578	.025	6	view →
CCRCC	DFS	Tertile	II,III,IV	0.795	1.000	.011	3	view →
HNSC	OS	Median	II,III,IV	0.656	0.906	.038	2	view →
LUAD	OS	Tertile	All	0.918	0.778	.036	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SLC15A2–UCEC (DFS)

Open the UCEC breakdown →