SLC15A1

Across TCGA pan-cancer cohorts, SLC15A1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SLC15A1 data layer compared with 21 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SLC15A1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC15A1 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

CCRCC and PDAC are the cancer types where SLC15A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	II,III,IV	0.379	0.833	.007	14	view →
PDAC	OS	Median	II,III,IV	0.574	0.418	.029	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

SLC15A1–CCRCC (DFS)

Open the CCRCC breakdown →