SLC15A1

Across TCGA patient cohorts, SLC15A1 mutation is significantly associated with the RNA expression of many other genes, with 3,393 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC15A1-associated genes across cancer lineages are ABALON, KLHL2, and PSMC3IP. Each is linked with SLC15A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC15A1-to-partner and partner-to-SLC15A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABALON grouped by SLC15A1-low versus SLC15A1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC15A1→partner) and Y-score (partner→SLC15A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ABALON →	+0.525	+3.062	<.001	<.001	3	3
UCEC	KLHL2 →	+0.463	+2.595	.005	<.001	3	3
UCEC	PSMC3IP →	+0.571	+2.686	<.001	<.001	3	3
UCEC	HAUS2 →	+0.527	+2.423	<.001	.001	3	3
UCEC	GPR180 →	+0.390	+1.789	.005	.008	3	3
COAD	SKA1 →	+0.631	+2.713	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,393 associations by consensus.

ABALON by SLC15A1 expression — SKCM

Explore this box plot interactively →