SLC14A2

Across TCGA patient cohorts, SLC14A2 mutation is significantly associated with the RNA expression of many other genes, with 5,857 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC14A2-associated genes across cancer lineages are SSRP1, CDCA2, and MZT1. Each is linked with SLC14A2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC14A2-to-partner and partner-to-SLC14A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SSRP1 grouped by SLC14A2-low versus SLC14A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC14A2→partner) and Y-score (partner→SLC14A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SSRP1 →	+0.464	+2.717	<.001	<.001	3	5
UCEC	CDCA2 →	+0.756	+2.321	<.001	<.001	3	4
UCEC	MZT1 →	+0.566	+1.516	<.001	.001	3	4
UCEC	C4orf46 →	+0.588	+3.353	<.001	<.001	3	4
STAD	COQ2 →	+0.539	+3.355	.003	.005	3	4
UCEC	DLAT →	+0.598	+2.321	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,857 associations by consensus.

SSRP1 by SLC14A2 expression — UCEC

Explore this box plot interactively →