SLC14A2

Across TCGA cell cohorts, SLC14A2 mutation is significantly associated with the RNA expression of many other genes, with 133 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC14A2-associated genes across cancer lineages are OR6B3, WFDC10A, and DCD. Each is linked with SLC14A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC14A2-to-partner and partner-to-SLC14A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6B3 grouped by SLC14A2-low versus SLC14A2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC14A2→partner) and Y-score (partner→SLC14A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR6B3 →	+0.041	+4.523	<.001	.004	3	2
UPPER_AERODIGESTIVE_TRACT	WFDC10A →	+0.047	+3.870	<.001	.003	3	2
BLOOD_Myeloma	DCD →	+0.063	+4.807	<.001	.006	3	1
BLOOD_Lymphoma	SULT2A1 →	+0.311	+4.523	<.001	.004	3	1
BLOOD_Lymphoma	PAX4 →	+0.053	+4.350	<.001	.005	3	1
BLOOD_Lymphoma	NOBOX →	+0.005	+5.247	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 133 associations by consensus.

OR6B3 by SLC14A2 expression — BLOOD_Lymphoma

Explore this box plot interactively →