SLC14A2-AS1

Across TCGA pan-cancer cohorts, SLC14A2-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of SLC14A2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SLC14A2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types SLC14A2-AS1 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and LUSC are the cancer types where SLC14A2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC14A2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	II,III,IV	−0.594	<.001	12	view →
KIRP	All	All	−0.513	<.001	9	view →
LUSC	Male	II,III,IV	−0.398	<.001	8	view →
BLCA	All	III,IV	−0.197	<.001	8	view →
HNSC	All	All	−0.037	.012	7	view →
BRCA	All	II,III,IV	−0.515	<.001	6	view →
LUAD	Female	II,III,IV	−0.294	.001	6	view →
COAD	Male	II,III,IV	−0.141	<.001	5	view →
LIHC	Male	All	+0.037	.016	5	view →
KICH	All	All	−0.331	.027	3	view →
THCA	Male	II,III,IV	−0.081	.008	3	view →
PAAD	Female	All	−0.155	.025	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

SLC14A2-AS1–KIRC

Open the KIRC breakdown →