SLC14A1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC14A1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,335 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SLC14A1-associated genes across cancer lineages are HBA1, LRR1, and TMEM159. Each is linked with SLC14A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC14A1-to-partner and partner-to-SLC14A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC14A1 versus HBA1 in LSCC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC14A1→partner) and Y-score (partner→SLC14A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCHBA1 →+1.492+0.714<.001<.00134
UCECLRR1 →-0.545-1.451.005.00233
GBMTMEM159 →-0.532-0.898<.001<.00133
CCRCCHBA2 →+1.530+0.879<.001<.00133
CCRCCHBB →+1.693+0.791<.001<.00133
UCECGINS1 →-0.821-1.246.007.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,335 associations by consensus.

SLC14A1 vs HBA1 — LSCC

Per-sample scatter of SLC14A1 vs HBA1 in LSCC (Pearson r = 0.52).

Explore this scatter interactively →

Exploration