SLC14A1

Across TCGA cell cohorts, SLC14A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,355 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SLC14A1-associated GO terms across cancer lineages are Regulation of angiotensin-activated signaling pathway, Biotin transport, and Response to transforming growth factor beta. Each is linked with SLC14A1 in more than 8 cancer types. Because this analysis shows association rather than direction, both SLC14A1-to-partner and partner-to-SLC14A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of angiotensin-activated signaling pathway grouped by SLC14A1-low versus SLC14A1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC14A1→partner) and Y-score (partner→SLC14A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of angiotensin-activated signaling pathway →	+0.213	+1.975	<.001	<.001	3	9
BONE	Biotin transport →	-0.318	-2.860	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Response to transforming growth factor beta →	+0.084	+0.821	.004	.007	3	7
BONE	Cellular response to transforming growth factor beta stimulus →	+0.077	+2.105	<.001	.007	3	7
LIVER	Transforming growth factor beta receptor signaling pathway →	+0.116	+2.963	.001	.002	3	7
SOFT_TISSUE	Protein dephosphorylation →	+0.059	+2.618	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,355 associations by consensus.

Regulation of angiotensin-activated signaling pathway by SLC14A1 expression — BONE

Explore this box plot interactively →