SLC13A5

Across TCGA patient cohorts, SLC13A5 mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC13A5-associated genes across cancer lineages are GAPDH, Src_pY527, and ATM. Each is linked with SLC13A5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC13A5-to-partner and partner-to-SLC13A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by SLC13A5-low versus SLC13A5-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC13A5→partner) and Y-score (partner→SLC13A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GAPDH →	+0.578	+2.321	.027	.033	3	3
UCEC	Src_pY527 →	-0.402	-2.690	.006	.006	3	3
UCEC	ATM →	-0.414	-2.102	.007	.016	3	3
UCEC	eEF2 →	+0.282	+1.247	.020	.045	3	2
UCEC	eIF4E →	+0.200	+1.807	.005	.004	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.389	-1.501	.011	.015	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

GAPDH by SLC13A5 expression — SKCM

Explore this box plot interactively →