SLC13A5

Across TCGA cell cohorts, SLC13A5 RNA expression is significantly associated with the go_rna of many other GO terms, with 818 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC13A5-associated GO terms across cancer lineages are Regulation of RNA splicing, Regulation of myoblast fusion, and Positive regulation of mRNA metabolic process. Each is linked with SLC13A5 in more than 6 cancer types. Because this analysis shows association rather than direction, both SLC13A5-to-partner and partner-to-SLC13A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of RNA splicing grouped by SLC13A5-low versus SLC13A5-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC13A5→partner) and Y-score (partner→SLC13A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of RNA splicing →	+0.065	+0.065	<.001	.001	3	7
LUNG_NSCLC_LUSC	Regulation of myoblast fusion →	+0.080	+0.174	.001	.004	3	6
LUNG_NSCLC_LUSC	Positive regulation of mRNA metabolic process →	+0.058	+0.160	.004	.006	3	6
LUNG_NSCLC_LUSC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.085	+0.178	.001	.003	3	6
LUNG_NSCLC_LUSC	Regulation of syncytium formation by plasma membrane fusion →	+0.077	+0.178	<.001	.003	3	6
STOMACH	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.040	-0.056	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 818 associations by consensus.

Regulation of RNA splicing by SLC13A5 expression — LARGE_INTESTINE

Explore this box plot interactively →