SLC13A5

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC13A5 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC13A5-associated genes across cancer lineages are FAM205A, OR2A5, and C5orf67. Each is linked with SLC13A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC13A5-to-partner and partner-to-SLC13A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM205A grouped by SLC13A5-low versus SLC13A5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC13A5→partner) and Y-score (partner→SLC13A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEFAM205A →+0.014+2.444.003.00832
STOMACHOR2A5 →+0.046+3.632<.001.00931
STOMACHC5orf67 →+0.144+3.432<.001.00831
LARGE_INTESTINEMAGEB4 →+0.011+3.415<.001.00131
LARGE_INTESTINEULBP3 →+0.952+3.064.002.00931
LARGE_INTESTINEADAM21 →+0.626+3.064<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

FAM205A by SLC13A5 expression — LARGE_INTESTINE

Box plot of FAM205A in SLC13A5-low vs SLC13A5-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration