SLC13A4

Across TCGA cell cohorts, SLC13A4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,477 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC13A4-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Negative regulation of myoblast fusion. Each is linked with SLC13A4 in more than 13 cancer types. Because this analysis shows association rather than direction, both SLC13A4-to-partner and partner-to-SLC13A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by SLC13A4-low versus SLC13A4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC13A4→partner) and Y-score (partner→SLC13A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.090	+0.459	.001	.002	3	14
BONE	Negative regulation of syncytium formation by plasma membrane fusion →	+0.104	+0.572	.001	.002	3	14
BONE	Negative regulation of myoblast fusion →	+0.105	+0.577	.001	.002	3	14
SKIN	Negative regulation of translational initiation →	+0.079	+0.372	<.001	.007	3	12
STOMACH	Pre-mRNA catabolic process →	+0.178	+0.676	<.001	<.001	3	11
LARGE_INTESTINE	Nuclear-transcribed mRNA catabolic process →	+0.051	+0.717	<.001	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,477 associations by consensus.

Regulation of myoblast fusion by SLC13A4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →