SLC13A4

Across TCGA cell cohorts, SLC13A4 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC13A4-associated genes across cancer lineages are OC90, F11, and EPPIN. Each is linked with SLC13A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC13A4-to-partner and partner-to-SLC13A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OC90 grouped by SLC13A4-low versus SLC13A4-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC13A4→partner) and Y-score (partner→SLC13A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OC90 →	+0.013	+4.371	<.001	.005	3	2
LARGE_INTESTINE	F11 →	+0.033	+3.297	.006	.002	3	2
BLOOD_Leukemia	EPPIN →	+0.006	+5.507	<.001	<.001	3	1
BLOOD_Leukemia	GPR26 →	+0.057	+4.539	<.001	.007	3	1
BLOOD_Leukemia	LYZL4 →	+0.104	+4.152	<.001	.009	3	1
BLOOD_Leukemia	OR1N2 →	+0.039	+4.705	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

OC90 by SLC13A4 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →