SLC13A3

Across TCGA cell cohorts, SLC13A3 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC13A3-associated genes across cancer lineages are PRSS45P, VAX1, and KRTAP1-4. Each is linked with SLC13A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC13A3-to-partner and partner-to-SLC13A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRSS45P grouped by SLC13A3-low versus SLC13A3-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC13A3→partner) and Y-score (partner→SLC13A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PRSS45P →	+0.017	+4.415	<.001	.007	3	2
LARGE_INTESTINE	VAX1 →	+0.535	+3.285	.004	.007	3	2
OESOPHAGUS	KRTAP1-4 →	+0.143	+4.906	<.001	.006	3	1
SKIN	OR13C5 →	+0.017	+5.022	<.001	.002	3	1
STOMACH	MYL10 →	+0.248	+4.129	<.001	.007	3	1
STOMACH	NCR1 →	+0.074	+4.129	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

PRSS45P by SLC13A3 expression — SKIN

Explore this box plot interactively →