SLC12A9

Across TCGA pan-cancer cohorts, SLC12A9 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC12A9 data layer compared with 26 for mass-spec protein and 11 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SLC12A9 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC12A9 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

CCRCC, LSCC, and LUAD are the cancer types where SLC12A9 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	IV	0.113	0.961	.024	13	view →
LSCC	DFS	Quartile	III,IV	1.000	0.399	.015	10	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	7	view →
PDAC	DFS	Tertile	IV	0.221	0.777	.024	5	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC12A9–CCRCC (DFS)

Open the CCRCC breakdown →