Across TCGA cell cohorts, SLC12A8 mutation is significantly associated with the RNA expression of many other genes, with 71 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC12A8-associated genes across cancer lineages are TEX55, OR7G2, and HES3. Each is linked with SLC12A8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC12A8-to-partner and partner-to-SLC12A8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC12A8→partner) and Y-score (partner→SLC12A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	TEX55 →	+0.037	+4.321	<.001	.009	3	1
CNS	OR7G2 →	+0.047	+4.754	<.001	.005	3	1
CNS	HES3 →	+0.032	+4.321	<.001	.009	3	1
CNS	OR11H6 →	+0.016	+4.321	.001	.009	3	1
CNS	FAM90A26 →	+0.006	+5.044	<.001	.001	3	1
LUNG_NSCLC_LUAD	MYOD1 →	+0.055	+3.977	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 71 associations by consensus.

Exploration

SLC12A8 survival (RNA) · tumor vs normal (RNA) · all SLC12A8 data types