SLC12A7

Across TCGA cell cohorts, SLC12A7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,240 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC12A7-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with SLC12A7 in more than 10 cancer types. Because this analysis shows association rather than direction, both SLC12A7-to-partner and partner-to-SLC12A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by SLC12A7-low versus SLC12A7-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC12A7→partner) and Y-score (partner→SLC12A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of myoblast fusion →	+0.086	+1.902	<.001	<.001	3	11
LUNG_SCLC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.098	+1.793	.001	.003	3	11
URINARY_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.077	+1.798	<.001	.004	3	11
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.076	+1.759	<.001	<.001	3	10
OESOPHAGUS	Glycerophospholipid metabolic process →	+0.043	+1.653	<.001	.003	3	10
OESOPHAGUS	Phospholipid biosynthetic process →	+0.056	+1.432	<.001	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,240 associations by consensus.

Negative regulation of myoblast fusion by SLC12A7 expression — BLOOD_Lymphoma

Explore this box plot interactively →