SLC12A7

Across TCGA cell cohorts, SLC12A7 mutation is significantly associated with the RNA expression of many other genes, with 775 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC12A7-associated genes across cancer lineages are CD1A, OR10W1, and MTFMT. Each is linked with SLC12A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC12A7-to-partner and partner-to-SLC12A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD1A grouped by SLC12A7-low versus SLC12A7-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC12A7→partner) and Y-score (partner→SLC12A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CD1A →	+0.019	+3.584	<.001	.004	3	2
LARGE_INTESTINE	OR10W1 →	+0.007	+2.655	<.001	.001	3	2
LARGE_INTESTINE	MTFMT →	+0.459	+2.628	.007	.002	3	2
LARGE_INTESTINE	MAPK8 →	+0.703	+2.800	.001	.001	3	2
LARGE_INTESTINE	KCTD20 →	+0.633	+2.628	<.001	.002	3	2
BLOOD_Leukemia	TTC33 →	+0.699	+3.470	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 775 associations by consensus.

CD1A by SLC12A7 expression — SOFT_TISSUE

Explore this box plot interactively →