SLC12A6

Across TCGA cell cohorts, SLC12A6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,364 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC12A6-associated GO terms across cancer lineages are Hypotonic salinity response, Cellular hypotonic salinity response, and Negative regulation of myoblast fusion. Each is linked with SLC12A6 in more than 18 cancer types. Because this analysis shows association rather than direction, both SLC12A6-to-partner and partner-to-SLC12A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hypotonic salinity response grouped by SLC12A6-low versus SLC12A6-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC12A6→partner) and Y-score (partner→SLC12A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Hypotonic salinity response →	+1.297	+1.891	<.001	<.001	3	19
BLOOD_Myeloma	Cellular hypotonic salinity response →	+1.297	+1.891	<.001	<.001	3	19
LARGE_INTESTINE	Negative regulation of myoblast fusion →	+0.117	+1.098	<.001	<.001	3	16
LARGE_INTESTINE	Regulation of syncytium formation by plasma membrane fusion →	+0.090	+0.997	<.001	<.001	3	15
LARGE_INTESTINE	Regulation of organelle assembly →	+0.048	+1.147	<.001	<.001	3	15
OESOPHAGUS	Golgi vesicle transport →	+0.068	+0.999	.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,364 associations by consensus.

Hypotonic salinity response by SLC12A6 expression — BLOOD_Myeloma

Explore this box plot interactively →