SLC12A5

Across TCGA cell cohorts, SLC12A5 mutation is significantly associated with the RNA expression of many other genes, with 478 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC12A5-associated genes across cancer lineages are BRDT, C1QTNF9, and CENPVL1. Each is linked with SLC12A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC12A5-to-partner and partner-to-SLC12A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BRDT grouped by SLC12A5-low versus SLC12A5-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC12A5→partner) and Y-score (partner→SLC12A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	BRDT →	+0.133	+4.342	<.001	.002	3	2
BLOOD_Leukemia	C1QTNF9 →	+0.042	+4.174	<.001	.001	3	2
OESOPHAGUS	CENPVL1 →	+0.246	+4.906	<.001	.006	3	1
LUNG_SCLC	WFDC10A →	+0.611	+3.232	.001	.008	3	1
LUNG_SCLC	SLC36A3 →	+0.014	+3.584	<.001	.003	3	1
BLOOD_Leukemia	BTBD16 →	+0.099	+4.281	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 478 associations by consensus.

BRDT by SLC12A5 expression — BLOOD_Leukemia

Explore this box plot interactively →