SLC12A3

Across TCGA patient cohorts, SLC12A3 protein abundance is significantly associated with the RNA expression of many other genes, with 15,066 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLC12A3-associated genes across cancer lineages are KDELR3, HMOX1, and ALKBH1. Each is linked with SLC12A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC12A3-to-partner and partner-to-SLC12A3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC12A3 versus KDELR3 in CCRCC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC12A3→partner) and Y-score (partner→SLC12A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	KDELR3 →	-0.625	-0.346	.001	<.001	3	1
CCRCC	HMOX1 →	+0.560	+0.421	<.001	<.001	3	1
CCRCC	ALKBH1 →	+0.229	+0.283	.001	.002	3	1
CCRCC	SRSF5 →	+0.328	+0.310	.001	.002	3	1
CCRCC	DICER1 →	+0.258	+0.386	<.001	<.001	3	1
CCRCC	NDRG3 →	-0.257	-0.394	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,066 associations by consensus.

SLC12A3 vs KDELR3 — CCRCC

Explore this scatter interactively →