SLC12A1

Across TCGA cell cohorts, SLC12A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,764 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC12A1-associated GO terms across cancer lineages are Regulation of phospholipid translocation, Positive regulation of phospholipid translocation, and Regulation of cell cycle G1/S phase transition. Each is linked with SLC12A1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SLC12A1-to-partner and partner-to-SLC12A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of phospholipid translocation grouped by SLC12A1-low versus SLC12A1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC12A1→partner) and Y-score (partner→SLC12A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of phospholipid translocation →	-0.083	-0.101	.001	<.001	3	7
BLOOD_Leukemia	Positive regulation of phospholipid translocation →	-0.083	-0.101	.001	<.001	3	7
BLOOD_Leukemia	Regulation of cell cycle G1/S phase transition →	+0.033	+0.097	.002	.005	3	6
BLOOD_Leukemia	Regulation of G1/S transition of mitotic cell cycle →	+0.033	+0.100	.002	.003	3	6
BLOOD_Leukemia	Protein polyubiquitination →	+0.015	+0.082	.002	.001	3	6
BLOOD_Leukemia	CTP salvage →	+0.080	+0.109	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,764 associations by consensus.

Regulation of phospholipid translocation by SLC12A1 expression — BLOOD_Leukemia

Explore this box plot interactively →