SLC11A2

Across TCGA patient cohorts, SLC11A2 mutation is significantly associated with the RNA expression of many other genes, with 3,183 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC11A2-associated genes across cancer lineages are RN7SL228P, RN7SKP230, and OR5M4P. Each is linked with SLC11A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC11A2-to-partner and partner-to-SLC11A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL228P grouped by SLC11A2-low versus SLC11A2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC11A2→partner) and Y-score (partner→SLC11A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL228P →	+0.082	+4.993	<.001	.002	3	2
SKCM	RN7SKP230 →	+0.301	+3.588	<.001	.009	3	2
BLCA	OR5M4P →	+0.055	+6.618	<.001	.001	3	2
CESC	MIR3135A →	+0.460	+4.503	.001	.005	3	2
UCEC	RN7SL134P →	+0.085	+1.899	.002	.002	3	2
BLCA	RNA5SP443 →	+0.424	+5.329	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,183 associations by consensus.

RN7SL228P by SLC11A2 expression — SKCM

Explore this box plot interactively →