SLC11A2

Across TCGA cell cohorts, SLC11A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,528 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC11A2-associated GO terms across cancer lineages are Oocyte growth, Glycerophospholipid metabolic process, and Regulation of macroautophagy. Each is linked with SLC11A2 in more than 11 cancer types. Because this analysis shows association rather than direction, both SLC11A2-to-partner and partner-to-SLC11A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oocyte growth grouped by SLC11A2-low versus SLC11A2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC11A2→partner) and Y-score (partner→SLC11A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Oocyte growth →	+0.190	+0.854	<.001	<.001	3	12
CNS	Glycerophospholipid metabolic process →	+0.052	+0.609	<.001	<.001	3	11
BLOOD_Lymphoma	Regulation of macroautophagy →	+0.056	+1.146	<.001	<.001	3	11
BREAST	Cytosolic transport →	+0.055	+0.723	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Intracellular manganese ion homeostasis →	+0.178	+0.920	.001	.009	3	11
CNS	Phospholipid biosynthetic process →	+0.046	+0.757	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,528 associations by consensus.

Oocyte growth by SLC11A2 expression — SKIN

Explore this box plot interactively →