SLC11A1

Across TCGA cell cohorts, SLC11A1 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC11A1-associated genes across cancer lineages are CPXCR1, AQP12A, and OR1J2. Each is linked with SLC11A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC11A1-to-partner and partner-to-SLC11A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CPXCR1 grouped by SLC11A1-low versus SLC11A1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC11A1→partner) and Y-score (partner→SLC11A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CPXCR1 →	+0.068	+3.456	<.001	<.001	3	1
BLOOD_Leukemia	AQP12A →	+0.092	+3.362	<.001	.001	3	1
BLOOD_Leukemia	OR1J2 →	+0.048	+3.181	.004	.001	3	1
BLOOD_Leukemia	TEDDM1 →	+0.062	+3.295	<.001	.009	3	1
BLOOD_Leukemia	ACSM4 →	+0.028	+2.556	.001	.007	3	1
BLOOD_Leukemia	OR6J1 →	+0.037	+2.556	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

CPXCR1 by SLC11A1 expression — BLOOD_Leukemia

Explore this box plot interactively →