SLC10A7

Across TCGA patient cohorts, SLC10A7 mutation is significantly associated with the RNA expression of many other genes, with 2,013 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC10A7-associated genes across cancer lineages are RNU6-169P, CYCSP44, and TMEM138. Each is linked with SLC10A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC10A7-to-partner and partner-to-SLC10A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-169P grouped by SLC10A7-low versus SLC10A7-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC10A7→partner) and Y-score (partner→SLC10A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	RNU6-169P →	+0.323	+7.977	<.001	.007	3	2
LUAD	CYCSP44 →	+0.302	+4.314	<.001	.003	3	2
UCEC	TMEM138 →	+0.258	+2.470	.001	<.001	3	2
UCEC	ART3 →	-0.402	-2.459	.008	<.001	3	2
UCEC	DAPK3 →	+0.461	+3.095	<.001	<.001	3	2
UCEC	REEP4 →	+0.532	+2.949	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,013 associations by consensus.

RNU6-169P by SLC10A7 expression — LGG

Explore this box plot interactively →