SLC10A7

Across TCGA patient cohorts, SLC10A7 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC10A7-associated genes across cancer lineages are PCNA, TFRC, and 4E-BP1. Each is linked with SLC10A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC10A7-to-partner and partner-to-SLC10A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by SLC10A7-low versus SLC10A7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC10A7→partner) and Y-score (partner→SLC10A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.268	+3.247	.001	<.001	3	2
UCEC	TFRC →	+0.445	+2.321	.029	.034	3	2
UCEC	4E-BP1 →	+0.239	+2.321	.021	.033	3	2
UCEC	EGFR →	-0.169	-3.700	.005	.001	3	1
UCEC	A-Raf_pS299 →	-0.137	-1.678	.002	.023	3	1
UCEC	INPP4B →	-0.349	-3.584	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

PCNA by SLC10A7 expression — UCEC

Explore this box plot interactively →