SLC10A7

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC10A7 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC10A7-associated genes across cancer lineages are HSFY2 and CD300H. Each is linked with SLC10A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC10A7-to-partner and partner-to-SLC10A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSFY2 grouped by SLC10A7-low versus SLC10A7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC10A7→partner) and Y-score (partner→SLC10A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEHSFY2 →+0.023+4.977<.001.00731
LARGE_INTESTINECD300H →+0.045+5.415<.001.00431
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

HSFY2 by SLC10A7 expression — LARGE_INTESTINE

Box plot of HSFY2 in SLC10A7-low vs SLC10A7-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration