SLC10A5

Across TCGA patient cohorts, SLC10A5 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC10A5-associated genes across cancer lineages are ATM, p62 Lck ligand, and AMPK_pT172. Each is linked with SLC10A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC10A5-to-partner and partner-to-SLC10A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by SLC10A5-low versus SLC10A5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC10A5→partner) and Y-score (partner→SLC10A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.397	-2.115	.045	.019	3	2
UCEC	p62 Lck ligand →	+0.344	+3.594	.015	.001	3	1
UCEC	AMPK_pT172 →	+0.480	+2.820	.007	.001	3	1
UCEC	TIGAR →	+0.149	+3.933	.025	<.001	3	1
UCEC	c-Kit →	-0.215	-2.115	.035	.019	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

ATM by SLC10A5 expression — UCEC

Explore this box plot interactively →