SLC10A5

Across TCGA cell cohorts, SLC10A5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,042 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible SLC10A5-associated GO terms across cancer lineages are Negative regulation of hematopoietic stem cell differentiation, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, and Promoter clearance during DNA-templated transcription. Each is linked with SLC10A5 in more than 8 cancer types. Because this analysis shows association rather than direction, both SLC10A5-to-partner and partner-to-SLC10A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of hematopoietic stem cell differentiation grouped by SLC10A5-low versus SLC10A5-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC10A5→partner) and Y-score (partner→SLC10A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of hematopoietic stem cell differentiation →	+0.190	+0.504	<.001	.005	3	9
LUNG_SCLC	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.087	+0.608	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Promoter clearance during DNA-templated transcription →	+0.118	+0.386	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	RNA polymerase II promoter clearance →	+0.118	+0.386	<.001	<.001	3	8
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.088	+0.198	.001	.001	3	8
BLOOD_Lymphoma	Regulation of RNA splicing →	+0.068	+0.209	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,042 associations by consensus.

Negative regulation of hematopoietic stem cell differentiation by SLC10A5 expression — OESOPHAGUS

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