SLC10A5

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC10A5 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC10A5-associated genes across cancer lineages are BTNL2, IQCF6, and OR12D2. Each is linked with SLC10A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC10A5-to-partner and partner-to-SLC10A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BTNL2 grouped by SLC10A5-low versus SLC10A5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC10A5→partner) and Y-score (partner→SLC10A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEBTNL2 →+0.081+4.415<.001.00731
LARGE_INTESTINEIQCF6 →+0.322+4.467<.001.00431
LARGE_INTESTINEOR12D2 →+0.103+4.467<.001.00431
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

BTNL2 by SLC10A5 expression — LARGE_INTESTINE

Box plot of BTNL2 in SLC10A5-low vs SLC10A5-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration