SLC10A4

Across TCGA cell cohorts, SLC10A4 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC10A4-associated genes across cancer lineages are ASB17, GFRA4, and KCNU1. Each is linked with SLC10A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC10A4-to-partner and partner-to-SLC10A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB17 grouped by SLC10A4-low versus SLC10A4-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC10A4→partner) and Y-score (partner→SLC10A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ASB17 →	+0.023	+5.807	<.001	.001	3	1
LARGE_INTESTINE	GFRA4 →	+0.025	+4.345	<.001	<.001	3	1
LARGE_INTESTINE	KCNU1 →	+0.057	+3.345	<.001	.007	3	1
LARGE_INTESTINE	CFHR2 →	+0.038	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

ASB17 by SLC10A4 expression — OVARY

Explore this box plot interactively →