SLC10A2

Across TCGA patient cohorts, SLC10A2 mutation is significantly associated with the RNA expression of many other genes, with 1,715 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC10A2-associated genes across cancer lineages are MRPS11, NOP10, and EIF3J. Each is linked with SLC10A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC10A2-to-partner and partner-to-SLC10A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRPS11 grouped by SLC10A2-low versus SLC10A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC10A2→partner) and Y-score (partner→SLC10A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MRPS11 →	+0.419	+2.407	.001	.003	3	3
UCEC	NOP10 →	+0.518	+3.000	<.001	.001	3	3
UCEC	EIF3J →	+0.571	+3.332	.001	.005	3	3
UCEC	LRRC59 →	+0.581	+3.592	.001	.001	3	3
UCEC	TUBG1 →	+0.555	+3.470	.003	.002	3	3
UCEC	RNU6-927P →	+0.212	+2.434	.002	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,715 associations by consensus.

MRPS11 by SLC10A2 expression — UCEC

Explore this box plot interactively →