SLC10A2

Across TCGA patient cohorts, SLC10A2 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC10A2-associated genes across cancer lineages are TFRC, Bcl-2, and 4E-BP1_pS65. Each is linked with SLC10A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC10A2-to-partner and partner-to-SLC10A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by SLC10A2-low versus SLC10A2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC10A2→partner) and Y-score (partner→SLC10A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TFRC →	+0.506	+1.530	.002	.003	3	3
SKCM	Bcl-2 →	-0.243	-1.874	.025	.047	3	3
SKCM	4E-BP1_pS65 →	+0.134	+1.427	.025	.025	3	2
UCEC	PDCD4 →	-0.578	-2.000	.006	.032	3	2
UCEC	PR →	-0.229	-3.169	.043	.018	3	2
UCEC	STAT3_pY705 →	-0.400	-2.000	<.001	.032	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

TFRC by SLC10A2 expression — SKCM

Explore this box plot interactively →