SLC10A2

Across TCGA cell cohorts, SLC10A2 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SLC10A2-associated genes across cancer lineages are AVP, KRT33A, and OR5A1. Each is linked with SLC10A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC10A2-to-partner and partner-to-SLC10A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by SLC10A2-low versus SLC10A2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC10A2→partner) and Y-score (partner→SLC10A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AVP →	+0.068	+4.217	<.001	.001	3	1
BLOOD_Lymphoma	KRT33A →	+0.009	+4.643	<.001	.005	3	1
LUNG_SCLC	OR5A1 →	+0.063	+4.523	.001	.003	3	1
LUNG_SCLC	TRIM60 →	+0.005	+4.643	<.001	.004	3	1
LUNG_SCLC	OR5T2 →	+0.015	+4.643	<.001	.004	3	1
LUNG_NSCLC_LUAD	KRT28 →	+0.005	+3.544	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

AVP by SLC10A2 expression — LARGE_INTESTINE

Explore this box plot interactively →