SLC10A1

Across TCGA pan-cancer cohorts, SLC10A1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC10A1 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SLC10A1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC10A1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

LSCC, CCRCC, and PDAC are the cancer types where SLC10A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	III,IV	0.584	1.000	.005	26	view →
CCRCC	DFS	Median	All	0.904	0.708	.002	17	view →
PDAC	OS	Quartile	II,III,IV	0.402	0.984	.007	12	view →
LUAD	DFS	Quartile	All	1.000	0.705	.036	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC10A1–LSCC (DFS)

Open the LSCC breakdown →