SLC10A1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC10A1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC10A1-associated genes across cancer lineages are OR10R2 and IQCF5. Each is linked with SLC10A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC10A1-to-partner and partner-to-SLC10A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10R2 grouped by SLC10A1-low versus SLC10A1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC10A1→partner) and Y-score (partner→SLC10A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaOR10R2 →+1.948+4.551<.001.00431
BLOOD_LeukemiaIQCF5 →+0.108+5.786<.001<.00131
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR10R2 by SLC10A1 expression — BLOOD_Leukemia

Box plot of OR10R2 in SLC10A1-low vs SLC10A1-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration