SLC10A1

Across TCGA cell cohorts, SLC10A1 mutation is significantly associated with the mutation status of many other genes, with 2,006 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC10A1-associated genes across cancer lineages are ANK1, PLXND1, and UPF1. Each is linked with SLC10A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC10A1-to-partner and partner-to-SLC10A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANK1 grouped by SLC10A1-low versus SLC10A1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC10A1→partner) and Y-score (partner→SLC10A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ANK1 →	+2.870	+3.347	.009	.009	1	2
BLOOD_Leukemia	PLXND1 →	+2.906	+4.866	<.001	<.001	1	2
BLOOD_Leukemia	UPF1 →	+3.063	+3.498	.006	.006	1	2
BLOOD_Leukemia	TCF3 →	+2.963	+3.960	.001	.001	1	2
BLOOD_Leukemia	ACTB →	+3.063	+3.498	.006	.006	1	2
BLOOD_Leukemia	SRCAP →	+2.285	+3.364	.006	.006	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,006 associations by consensus.

ANK1 by SLC10A1 expression — BLOOD_Leukemia

Explore this box plot interactively →