SLAMF7

Across TCGA patient cohorts, SLAMF7 protein abundance is significantly associated with the RNA expression of many other genes, with 9,858 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLAMF7-associated genes across cancer lineages are PIM2, FCRL5, and PNOC. Each is linked with SLAMF7 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLAMF7-to-partner and partner-to-SLAMF7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLAMF7 versus PIM2 in LSCC, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLAMF7→partner) and Y-score (partner→SLAMF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PIM2 →	+1.098	+0.683	<.001	<.001	3	4
LSCC	FCRL5 →	+1.378	+0.700	<.001	<.001	3	4
HNSC	PNOC →	+1.001	+0.608	.002	<.001	3	4
HNSC	NUGGC →	+1.322	+0.607	.007	.001	3	4
HNSC	IGKJ5 →	+2.335	+0.569	.005	.001	3	4
BRCA	IGKV5-2 →	+2.225	+0.766	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,858 associations by consensus.

SLAMF7 vs PIM2 — LSCC

Explore this scatter interactively →