SLAMF6

Across TCGA cell cohorts, SLAMF6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,526 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLAMF6-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and Positive regulation of T-helper 17 cell differentiation. Each is linked with SLAMF6 in more than 6 cancer types. Because this analysis shows association rather than direction, both SLAMF6-to-partner and partner-to-SLAMF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cellular anatomical structure grouped by SLAMF6-low versus SLAMF6-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLAMF6→partner) and Y-score (partner→SLAMF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Symbiont-mediated disruption of host cellular anatomical structure →	+0.079	+1.925	<.001	.001	3	7
BLOOD_Lymphoma	Symbiont-mediated disruption of host anatomical structure →	+0.079	+1.925	<.001	.001	3	7
BLOOD_Myeloma	Positive regulation of T-helper 17 cell differentiation →	+0.128	+1.811	.001	.007	3	5
BLOOD_Lymphoma	Positive regulation of DNA metabolic process →	+0.035	+1.962	.001	.003	3	4
BREAST	Regulation of RNA polymerase II transcription preinitiation complex assembly →	+0.108	+0.018	.003	.003	3	4
BREAST	Centrosome cycle →	+0.052	+0.014	.007	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,526 associations by consensus.

Symbiont-mediated disruption of host cellular anatomical structure by SLAMF6 expression — BLOOD_Lymphoma

Explore this box plot interactively →