SLAMF1

Across TCGA pan-cancer cohorts, SLAMF1 mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SLAMF1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where SLAMF1 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types SLAMF1 is over-expressed in tumor, although a few such as PDAC show the opposite, repressed pattern.

LUAD, PDAC, and LSCC are the cancer types where SLAMF1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLAMF1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.625	<.001	6	view →
PDAC	All	All	−2.207	.013	1	view →
LSCC	Female	All	+0.481	.008	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

SLAMF1–LUAD

Open the LUAD breakdown →