SLAMF1

Across TCGA cell cohorts, SLAMF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,348 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLAMF1-associated GO terms across cancer lineages are Membrane raft localization, Energy coupled proton transmembrane transport, against electrochemical gradient, and Electron transport coupled proton transport. Each is linked with SLAMF1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLAMF1-to-partner and partner-to-SLAMF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Membrane raft localization grouped by SLAMF1-low versus SLAMF1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLAMF1→partner) and Y-score (partner→SLAMF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Membrane raft localization →	-0.135	-0.030	<.001	.001	3	5
LIVER	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.054	+0.077	.003	.007	3	5
LIVER	Electron transport coupled proton transport →	+0.054	+0.077	.003	.007	3	5
BLOOD_Leukemia	Positive regulation of lymphocyte activation →	+0.030	+1.811	.006	<.001	3	4
BLOOD_Lymphoma	Reduction of food intake in response to dietary excess →	+0.802	+3.331	<.001	<.001	3	4
BLOOD_Lymphoma	Cellular response to peptide hormone stimulus →	+0.030	+2.416	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,348 associations by consensus.

Membrane raft localization by SLAMF1 expression — LARGE_INTESTINE

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