SLAIN2

Across TCGA patient cohorts, SLAIN2 mutation is significantly associated with the RNA expression of many other genes, with 941 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLAIN2-associated genes across cancer lineages are MIR520C, RNU6-1318P, and RNA5SP164. Each is linked with SLAIN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLAIN2-to-partner and partner-to-SLAIN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR520C grouped by SLAIN2-low versus SLAIN2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLAIN2→partner) and Y-score (partner→SLAIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR520C →	+0.564	+4.704	<.001	.005	3	2
UCEC	RNU6-1318P →	+0.284	+2.658	<.001	.005	3	2
UCEC	RNA5SP164 →	+0.107	+4.153	<.001	.005	3	2
UCEC	RNU6-965P →	+0.233	+4.153	<.001	.005	3	2
COAD	RNU6-7 →	+0.382	+4.173	.005	.003	3	2
SKCM	TEX36-AS1 →	+0.041	+4.624	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 941 associations by consensus.

MIR520C by SLAIN2 expression — BLCA

Explore this box plot interactively →