SLAIN2

Across TCGA cell cohorts, SLAIN2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLAIN2-associated genes across cancer lineages are LCE1F and LEUTX. Each is linked with SLAIN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLAIN2-to-partner and partner-to-SLAIN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCE1F grouped by SLAIN2-low versus SLAIN2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLAIN2→partner) and Y-score (partner→SLAIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LCE1F →	+0.122	+4.415	<.001	.007	3	1
CNS	LEUTX →	+0.226	+5.321	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

LCE1F by SLAIN2 expression — LARGE_INTESTINE

Explore this box plot interactively →