SLA

Across TCGA patient cohorts, SLA RNA expression is significantly associated with the protein abundance of many other proteins, with 21,100 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SLA-associated proteins across cancer lineages are ARHGAP15_S64, ARHGAP25, and ARHGAP30. Each is linked with SLA in more than 9 cancer types. Because this analysis shows association rather than direction, both SLA-to-partner and partner-to-SLA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLA versus ARHGAP15_S64 in LSCC, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLA→partner) and Y-score (partner→SLA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGAP15_S64 →	+1.213	+0.899	<.001	<.001	3	10
OV	ARHGAP25 →	+0.910	+1.151	<.001	<.001	3	10
UCEC	ARHGAP30 →	+0.701	+0.937	<.001	<.001	3	10
GBM	PARVG →	+0.717	+1.211	<.001	<.001	3	10
GBM	ARHGAP4 →	+0.574	+1.260	<.001	<.001	3	10
GBM	ARHGAP45 →	+0.691	+1.226	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,100 associations by consensus.

SLA vs ARHGAP15_S64 — LSCC

Explore this scatter interactively →