SLA

Across TCGA cell cohorts, SLA RNA expression is significantly associated with the go_rna of many other GO terms, with 2,165 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLA-associated GO terms across cancer lineages are Golgi vesicle transport, Negative regulation of myoblast fusion, and Negative regulation of TOR signaling. Each is linked with SLA in more than 5 cancer types. Because this analysis shows association rather than direction, both SLA-to-partner and partner-to-SLA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by SLA-low versus SLA-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLA→partner) and Y-score (partner→SLA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Golgi vesicle transport →	+0.051	+0.105	<.001	<.001	3	6
LARGE_INTESTINE	Negative regulation of myoblast fusion →	+0.084	+0.092	<.001	.002	3	6
LARGE_INTESTINE	Negative regulation of TOR signaling →	+0.047	+0.109	<.001	.002	3	6
LARGE_INTESTINE	Negative regulation of syncytium formation by plasma membrane fusion →	+0.077	+0.087	<.001	.003	3	6
BLOOD_Leukemia	Peptidyl-serine autophosphorylation →	+0.084	+2.160	<.001	<.001	3	6
LARGE_INTESTINE	Regulation of syncytium formation by plasma membrane fusion →	+0.056	+0.079	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,165 associations by consensus.

Golgi vesicle transport by SLA expression — LARGE_INTESTINE

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